3-Methoxyeticyclidine (3-MeO-PCE) is a dissociative drug chemically related to PCP and ketamine. Recreational drug users have enjoyed its unique effects in recent years, which include feelings of dissociation, euphoria, and self-reflection. In this article, we’ll examine the history of 3-MeO-PCE, dosage information, user experience, and potential side effects. By better understanding this drug, readers can make informed decisions about its use and better understand the potential risks and benefits associated with 3-MeO-PCE.

General Information on 3-MeO-PCE

To begin our research chemical review, let’s go over the basics of this drug. It belongs to the arylcyclohexylamine class of substances, which generally cause dissociation. 3-MeO-PCE is synthetic, meaning it’s not found in nature. It’s typically sold in powder or pellet form, and it can be taken orally, nasally, or via injection.

The drug is known for its dissociative effects, which can include feelings of detachment, sensory distortion, and altered states of consciousness. It also has stimulant-like effects, which can include increased heart rate, blood pressure, and body temperature.

Due to its relative newness, there’s not much known about the long-term effects of 3-MeO-PCE use. As part of our 3-MeO-PCE review, it’s also key to note that this drug isn’t currently approved for medical use and is illegal in many countries. In the U.S., it’s classified as a Schedule I controlled substance. All Schedule I drugs are believed to have a high potential for abuse and aren’t accepted for medical use.

Overall, while 3-MeO-PCE is a little more well-known now among some recreational drug users, you should understand the potential risks associated with its use and exercise caution when using this or any psychoactive substance.

History of 3-MeO-PCE

In the early 2000s, the pharmaceutical company Parke-Davis first synthesized 3-MeO-PCE. The drug was originally made for potential use as an anesthetic or analgesic. However, it was never marketed for medical use.

In the years following its creation, the 3-MeO-PCE research chemical began to pop up as a recreational drug in underground drug markets. Users appreciated its distinctive dissociative effects and its special ability to produce both stimulating and sedative effects.

Despite its increasing popularity, we don’t know much about the history of 3-MeO-PCE’s use as a recreational drug. The drug likely began to pick up traction in online drug communities in the early 2010s as its availability grew.

Today, as mentioned, 3-MeO-PCE is a Schedule I substance and is illegal in many other countries worldwide. So, users seeking legal drugs will most likely need to keep looking. There are many drugs to achieve legal highs that live in gray areas of the law, but this one has been clearly defined.

Dosage and Administration

The user’s weight, tolerance, and desired effects are all factors to consider when examining dosage and administration. However, you can follow some general guidelines, and we can learn a considerable amount from user reports.

As mentioned, 3-MeO-PCE can be taken orally, nasally, or through injection. The effects can last anywhere from 4 to 8 hours, depending on the administration and dosage.

It’s critical to start with a low dose. From there, gradually increase as needed to avoid adverse effects. Users should also avoid taking 3-MeO-PCE along with other drugs, as this can increase the risk of negative interactions and adverse effects.

Oral Administration

For oral consumption, a typical dosage range is between 5 and 20 milligrams. This can be taken in capsule or tablet form. Nasal consumption is a more potent method of administration and typically requires a lower dosage range of 2 to 10 milligrams.

Nasal Insufflation

Nasal insufflation, or snorting, can be painful for this drug. Users recommend doing a nasal rinse afterward to minimize the pain and drip. Insufflating this sharp and bitter powder can cause high levels of discomfort.

Vaporization

Vaporization involves heating the substance until it turns into gas or vapor, then inhaling it. When users vaporize 3-MeO-PCE, the onset is quick, but the effects wear off faster. Vaporizing this drug can be risky due to lung damage or toxic byproducts that we may not know about yet.

Injection

Injecting this drug is the most potent method of administration. So, users should exercise caution. The recommended dosage for injection is between 1 and 5 milligrams.

Redosing

Due to its unpredictability and potency, this drug generally shouldn’t be redosed. Redosing refers to taking more doses after the initial dose. Further, one dose may last up to 8 hours, so redosing may result in a duration that becomes troublesome for the user.

User 3-ME-PCE Reviews

Here are some general themes we find in user reports.

Many users report 3-MeO-PCE has strong dissociative effects that can produce feelings of detachment from reality, a warped sense of time and space, and alterations in sensory perception. One user described the body disorientation feeling as hanging outside a speeding car.

Some users have reported experiencing euphoria and a sense of peace when using 3-MeO-PCE. On the other hand, others have reported feeling agitated, anxious, or paranoid.

There have been reports of both positive and negative physical effects. Some users have reported increased heart rate, blood pressure, and body temperature, while others have reported nausea and other gastrointestinal issues.

Users also have reported negative psychological effects. Some users have reported experiencing anxiety, paranoia, and even psychosis after using the drug. It’s important to note these reports are based on individual experiences and may not represent the drug’s effects on everyone.

Onset of Effects

The onset of effects for 3-MeO-PCE can vary depending on several factors, including the user’s weight, tolerance, and route of administration. Here are some general guidelines:

• Oral consumption: The effects of 3-MeO-PCE can normally be felt within 30 to 60 minutes after ingestion.
• Nasal consumption: Users feel the effects within 10 to 30 minutes after ingestion.
• Injection: Users may feel the effects immediately, within a few seconds to a minute after injection.

Potential Side Effects of 3-ME-PCE

Here are some of the potential side effects of 3-MeO-PCE:

• Physical: increased heart rate, blood pressure, and body temperature; nausea, vomiting, and other gastrointestinal issues
• Psychological: dissociation, altered sense of reality, time, and space; anxiety, paranoia, and psychosis
• Cognitive: difficulty with memory, concentration, and decision-making
• Addiction: potential for addiction and dependence with long-term use

Notably, these side effects may not occur in all users, and the severity and duration of the effects might be different from person to person. Users should exercise caution when using 3-MeO-PCE. Always go to a healthcare professional with any concerns about the potential risks and side effects associated with the 3-MeO-PCE research chemical.