Pyrazolam Review


Are you curious about Pyrazolam? This “downer” research chemical has gained popularity among people who are intrigued by the effects of benzodiazepines. In this article, we’ll provide a comprehensive overview of Pyrazolam, also known as PZM or pyraz. We’ll outline its history, dosage, administration methods, user reviews, and potential side effects.

General Information on Pyrazolam

Let’s start off this research chemical review with general information on PZM. Basically, Pyrazolam is a benzodiazepine drug, which is a type of depressant. It was first created in the 1970s by a pharmaceutical company called Hoffmann-La Roche. Researcher Leo Sternbach led the research team that worked on this drug. It’s a triazolo-benzodiazepine, so it has a triazole ring on the benzodiazepine structure, which may help enhance the sedation effects. It’s classified as a research chemical and isn’t approved for human use.

Primarily, the PZM research chemical is known for its anxiolytic and sedative effects. Its chemical makeup is believed to influence the GABA receptor, which blocks neurotransmission within the central nervous system. In other words, Pyrazolam can impact the effects of GABA, resulting in feelings of relaxation and calmness.

History of Pyrazolam

Now, let’s cover some history as part of our Pyrazolam review. As you’ve already learned, Pyrazolam was first created in the 1970s. However, it wasn’t until the early 2010s that it became popular as a research chemical. The PZM research chemical may have first been sold online by a research chemical vendor in 2012, but this information isn’t conclusive.

Since then, Pyrazolam has risen in popularity to become one of the most prevalent benzodiazepine research chemicals on the market today. In many cases, it’s used in scientific research to study the benzodiazepine effects. Of course, there are also recreational users.

In many regions, PZM isn’t exactly on the list of legal drugs, but it’s not illegal, either. It exists in a legal gray area in many places as a result. Countries that do have it listed as a controlled substance are Canada, the UK, Turkey, Switzerland, and Sweden.

Dosage and Administration

So, what form does this drug usually come in, and what are the standard doses and administration methods? The PZM research chemical comes in powder form and is usually taken orally, in doses of 0.5 to 4mg. It can also be insufflated (snorted), vaporized, or used as a suppository. The dosage and administration methods change according to the user’s preferred effects and tolerance. Keep in mind that this is a research drug, and it’s not approved for human use, so dosage information isn’t concrete.

Oral Administration

The most common way to take Pyrazolam is via oral administration. As a powder, users can dissolve it in water or another liquid and swallow it. The effects normally begin within 20-30 minutes and they may last several hours.

Nasal Insufflation

Some users choose to insufflate Pyrazolam, which is when the user snorts it in powder form. Usually, the results hit faster with this method, but it can cause nasal irritation.


It’s possible to vaporize this drug by using a vaporizer or e-cigarette. Doing so allows for a quicker onset of effects and may be more efficient than taking it orally.


Some people choose to use Pyrazolam as a suppository. That means the powder is inserted into the rectum, allowing quick absorption into the bloodstream. While it’s not advisable for beginners, it does cause effects to settle in faster.


Like some other benzodiazepines, Pyrazolam has a long half-life. That means it can take several hours for the effects to wear off. So, redosing too soon can lead to overdose and other negative side effects. Users should wait at least 4-6 hours before redosing. On that note, due to this drug’s harmful interactions with other drugs, it’s important to keep track of what other medications may be in the mix. Do not redose and combine PZM with another drug, as the outcome could be fatal.

User Pyrazolam Reviews

Many people who have tried Pyrazolam report feeling relaxed, calm, and anxiety-free. Some report feeling euphoric and sociable. However, there may be some negative side effects, including drowsiness, dizziness, and memory impairment. While user reviews can be helpful, take them lightly because they are completely subjective and may not apply to everyone.

Onset of Effects

The onset of effects for Pyrazolam changes depending on how the drug was taken. Oral administration normally results in effects within 20-30 minutes. Insufflation and vaporization can result in a quicker onset of effects. The effects may endure several hours, and peak effects occur around 2-4 hours after administration.


The main effect of Pyrazolam, and the main reason people take it, is relaxation and sedation. People with anxiety, insomnia, and other sleep disorders may benefit from PZM. It can also help with muscle relaxation and can be used as an anticonvulsant.


While Pyrazolam is primarily known for its anxiolytic and sedative effects, some people feel euphoric after taking it. PZM may cause a sense of calmness and relaxation, which may lead to this reported euphoric feeling. Not everyone will experience euphoria when taking Pyrazolam. Some even take it hoping to feel euphoria and are disappointed when it has purely therapeutic effects. Also, note that euphoria is a subjective experience that varies from person to person, so some users may call a relaxed feeling “euphoria” while others wouldn’t label it as such.


Some users say they felt more friendly and talkative after taking Pyrazolam. This may be due to the drug’s ability to reduce inhibitions and anxiety, making it easier for people to interact with others. Also, the euphoric feelings Pyrazolam induces might contribute to sociability.

Anticlimax (“Comedown”)

As with many drugs, Pyrazolam can cause an anticlimax or “comedown” once the effects wear off. It can cause fatigue, depression, and irritability. Wait at least 24 hours before redosing to avoid negative side effects.

Potential Side Effects of Pyrazolam

While Pyrazolam is generally considered safe when used as directed, there are some potential side effects. These include the following:

  • Drowsiness
  • Dizziness
  • Memory impairment
  • Headache
  • Nausea
  • Diarrhea
  • Loss of appetite
  • Irritability
  • Agitation
  • Confusion
  • Respiratory depression
  • Seizures (in rare cases)

Use Pyrazolam responsibly and follow dosage guidelines carefully. Since PZM isn’t necessarily on the list of legal highs in many places, it may be difficult to take it under a medical professional, making it even more vital to be responsible. Remember, avoid using Pyrazolam with other depressant drugs and practice harm reduction techniques to help achieve the best outcome possible.

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